UPDATE: 8.38am March 30:

TWO men reported missing from Murwillumbah and Tweed Heads have been found safe and well.

Tweed/Byron LAC Inspector Mick Dempsey confirmed David Billis and Jamie Waldron had both been located. 

Initial report:

POLICE have appealed for assistance in finding two men who have been missing from the Tweed since last Monday.

Police have concerns for the welfare of both David Billis, 40, and Jamie Waldron, 45.

Despite both men going missing on Monday, the cases are unrelated.

Mr Bilis, described as caucasian, 6'2'' tall with hazel eyes, a new tattoo of a woman on his left arm, with short black, slicked-back hair and a goatee beard, was last seen in Tweed Heads on Monday, March 21.

He was wearing a dark blue Manchester United shirt, light blue shorts and runners at the time.

Mr Bilis suffers from a medical condition and was driving a silver coloured Nisan Bluebird sedan with Victorian registration NVE583.

Mr Waldron was also last seen on the same day, but in the Murwillumbah area.

Police said he may have been driving a white Lexus sedan with NSW registration BX19XL.

Anyone with information about the whereabouts of these two men should contact Tweed Heads Police Station on 07 5536 0999 or Crime Stoppers on 1800 333 000.